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Pseudomonas aeruginosa 4-Amino-4-Deoxychorismate Lyase: Spatial Conservation of an Active Site Tyrosine and Classification of Two Types of Enzyme
4-Amino-4-deoxychorismate lyase (PabC) catalyzes the formation of 4-aminobenzoate, and release of pyruvate, during folate biosynthesis. This is an essential activity for the growth of Gram-negative bacteria, including important pathogens such as Pseudomonas aeruginosa. A high-resolution (1.75 Å) cry...
Autores principales: | O'Rourke, Patrick E. F., Eadsforth, Thomas C., Fyfe, Paul K., Shepherd, Sharon M., Hunter, William N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174152/ https://www.ncbi.nlm.nih.gov/pubmed/21935381 http://dx.doi.org/10.1371/journal.pone.0024158 |
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