Protein-Protein Interactions in Crystals of the Human Receptor-Type Protein Tyrosine Phosphatase ICA512 Ectodomain

ICA512 (or IA-2) is a transmembrane protein-tyrosine phosphatase located in secretory granules of neuroendocrine cells. Initially, it was identified as one of the main antigens of autoimmune diabetes. Later, it was found that during insulin secretion, the cytoplasmic domain of ICA512 is cleaved and...

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Detalles Bibliográficos
Autores principales: Primo, María E., Jakoncic, Jean, Noguera, Martín E., Risso, Valeria A., Sosa, Laura, Sica, Mauricio P., Solimena, Michele, Poskus, Edgardo, Ermácora, Mario R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174154/
https://www.ncbi.nlm.nih.gov/pubmed/21935384
http://dx.doi.org/10.1371/journal.pone.0024191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174154/
https://www.ncbi.nlm.nih.gov/pubmed/21935384
http://dx.doi.org/10.1371/journal.pone.0024191

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