Impaired Thymic Export and Apoptosis Contribute to Regulatory T-Cell Defects in Patients with Chronic Heart Failure

OBJECTIVE: Animal studies suggest that regulatory T (T(reg)) cells play a beneficial role in ventricular remodeling and our previous data have demonstrated defects of T(reg) cells in patients with chronic heart failure (CHF). However, the mechanisms behind T(reg-)cell defects remained unknown. We he...

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Detalles Bibliográficos
Autores principales: Tang, Ting-Ting, Zhu, Zheng-Feng, Wang, Jun, Zhang, Wen-Cai, Tu, Xin, Xiao, Hong, Du, Xin-Ling, Xia, Jia-Hong, Dong, Nian-Guo, Su, Wei, Xia, Ni, Yan, Xing-Xing, Nie, Shao-Fang, Liu, Juan, Zhou, Su-Feng, Yao, Rui, Xie, Jiang-Jiao, Jevallee, Harish, Wang, Xiang, Liao, Meng-Yang, Shi, Guo-Ping, Fu, Michael, Liao, Yu-Hua, Cheng, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174174/
https://www.ncbi.nlm.nih.gov/pubmed/21935395
http://dx.doi.org/10.1371/journal.pone.0024272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174174/
https://www.ncbi.nlm.nih.gov/pubmed/21935395
http://dx.doi.org/10.1371/journal.pone.0024272

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