Study of FoxA Pioneer Factor at Silent Genes Reveals Rfx-Repressed Enhancer at Cdx2 and a Potential Indicator of Esophageal Adenocarcinoma Development

Understanding how silent genes can be competent for activation provides insight into development as well as cellular reprogramming and pathogenesis. We performed genomic location analysis of the pioneer transcription factor FoxA in the adult mouse liver and found that about one-third of the FoxA bou...

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Detalles Bibliográficos
Autores principales: Watts, Jason A., Zhang, Chaolin, Klein-Szanto, Andres J., Kormish, Jay D., Fu, Jian, Zhang, Michael Q., Zaret, Kenneth S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174211/
https://www.ncbi.nlm.nih.gov/pubmed/21935353
http://dx.doi.org/10.1371/journal.pgen.1002277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174211/
https://www.ncbi.nlm.nih.gov/pubmed/21935353
http://dx.doi.org/10.1371/journal.pgen.1002277

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