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Study of FoxA Pioneer Factor at Silent Genes Reveals Rfx-Repressed Enhancer at Cdx2 and a Potential Indicator of Esophageal Adenocarcinoma Development
Understanding how silent genes can be competent for activation provides insight into development as well as cellular reprogramming and pathogenesis. We performed genomic location analysis of the pioneer transcription factor FoxA in the adult mouse liver and found that about one-third of the FoxA bou...
Autores principales: | Watts, Jason A., Zhang, Chaolin, Klein-Szanto, Andres J., Kormish, Jay D., Fu, Jian, Zhang, Michael Q., Zaret, Kenneth S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174211/ https://www.ncbi.nlm.nih.gov/pubmed/21935353 http://dx.doi.org/10.1371/journal.pgen.1002277 |
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