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The Receptor Tyrosine Kinase Alk Controls Neurofibromin Functions in Drosophila Growth and Learning

Anaplastic Lymphoma Kinase (Alk) is a Receptor Tyrosine Kinase (RTK) activated in several cancers, but with largely unknown physiological functions. We report two unexpected roles for the Drosophila ortholog dAlk, in body size determination and associative learning. Remarkably, reducing neuronal dAl...

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Detalles Bibliográficos
Autores principales: Gouzi, Jean Y., Moressis, Anastasios, Walker, James A., Apostolopoulou, Anthi A., Palmer, Ruth H., Bernards, André, Skoulakis, Efthimios M. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174217/
https://www.ncbi.nlm.nih.gov/pubmed/21949657
http://dx.doi.org/10.1371/journal.pgen.1002281