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Luminal-Applied Flagellin Is Internalized by Polarized Intestinal Epithelial Cells and Elicits Immune Responses via the TLR5 Dependent Mechanism

Bacteria release flagellin that elicits innate responses via Toll-like receptor 5 (TLR5). Here, we investigated the fate of apically administrated full length flagellin from virulent and avirulent bacteria, along with truncated recombinant flagellin proteins in intestinal epithelial cells and cellul...

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Detalles Bibliográficos
Autores principales: Eaves-Pyles, Tonyia, Bu, Heng-Fu, Tan, Xiao-di, Cong, Yingzi, Patel, Jignesh, Davey, Robert A., Strasser, Jane E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174220/
https://www.ncbi.nlm.nih.gov/pubmed/21949773
http://dx.doi.org/10.1371/journal.pone.0024869