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Tuning arousal with optogenetic modulation of locus coeruleus neurons

Neural activity in the noradrenergic locus coeruleus correlates with periods of wakefulness and arousal. However, whether tonic or phasic activity in these neurons is necessary or sufficient to induce behavioral state transitions and promote long-term arousal is unresolved. We used optogenetic tools...

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Detalles Bibliográficos
Autores principales: Carter, Matthew E., Yizhar, Ofer, Chikahisa, Sachiko, Nguyen, Hieu, Adamantidis, Antoine, Nishino, Seiji, Deisseroth, Karl, de Lecea, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174240/
https://www.ncbi.nlm.nih.gov/pubmed/21037585
http://dx.doi.org/10.1038/nn.2682