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Tuning arousal with optogenetic modulation of locus coeruleus neurons
Neural activity in the noradrenergic locus coeruleus correlates with periods of wakefulness and arousal. However, whether tonic or phasic activity in these neurons is necessary or sufficient to induce behavioral state transitions and promote long-term arousal is unresolved. We used optogenetic tools...
Autores principales: | Carter, Matthew E., Yizhar, Ofer, Chikahisa, Sachiko, Nguyen, Hieu, Adamantidis, Antoine, Nishino, Seiji, Deisseroth, Karl, de Lecea, Luis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174240/ https://www.ncbi.nlm.nih.gov/pubmed/21037585 http://dx.doi.org/10.1038/nn.2682 |
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