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SPG20, a novel biomarker for early detection of colorectal cancer, encodes a regulator of cytokinesis

Colorectal cancer is a common disease with high mortality. Suitable biomarkers for detection of tumors at an early curable stage would significantly improve patient survival. Here, we show that the SPG20 (spastic paraplegia-20) promoter, encoding the multifunctional Spartin protein, is hypermethylat...

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Detalles Bibliográficos
Autores principales: Lind, G E, Raiborg, C, Danielsen, S A, Rognum, T O, Thiis-Evensen, E, Hoff, G, Nesbakken, A, Stenmark, H, Lothe, R A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174365/
https://www.ncbi.nlm.nih.gov/pubmed/21499309
http://dx.doi.org/10.1038/onc.2011.109