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Medicinal Chemistry and Actions of Dual and Pan PPAR Modulators

Peroxisome proliferator-activated receptor (PPAR) agonists are used as adjunct therapy in the treatment of diabetes mellitus. Fibrates, including fenofibrate, gemfibrozil, benzafibrate, ciprofibrate, and clofibrate act on PPAR alpha to reduce the level of hypertriglyceridemia. However, agonists (lig...

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Detalles Bibliográficos
Autores principales: Adeghate, Ernest, Adem, Abdu, Hasan, Mohamed Y, Tekes, Kornelia, Kalasz, Huba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Open 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174518/
https://www.ncbi.nlm.nih.gov/pubmed/21966330
http://dx.doi.org/10.2174/1874104501105010093