Mesenchymal stem cell transplantation ameliorates motor function deterioration of spinocerebellar ataxia by rescuing cerebellar Purkinje cells

BACKGROUND: Spinocerebellar ataxia (SCA) refers to a disease entity in which polyglutamine aggregates are over-produced in Purkinje cells (PCs) of the cerebellum as well as other neurons in the central nervous system, and the formation of intracellular polyglutamine aggregates result in the loss of...

Descripción completa

Detalles Bibliográficos
Autores principales: Chang, You-Kang, Chen, Ming-Hsiang, Chiang, Yi-Hung, Chen, Yu-Fan, Ma, Wei-Hsien, Tseng, Chian-You, Soong, Bin-Wen, Ho, Jennifer H, Lee, Oscar K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174876/
https://www.ncbi.nlm.nih.gov/pubmed/21824437
http://dx.doi.org/10.1186/1423-0127-18-54

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174876/
https://www.ncbi.nlm.nih.gov/pubmed/21824437
http://dx.doi.org/10.1186/1423-0127-18-54

Ejemplares similares