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Factor analysis of attentional set-shifting performance in young and aged mice

BACKGROUND: Executive dysfunction may play a major role in cognitive decline with aging because frontal lobe structures are particularly vulnerable to advancing age. Lesion studies in rats and mice have suggested that intradimensional shifts (IDSs), extradimensional shifts (EDSs), and reversal learn...

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Detalles Bibliográficos
Autores principales: Tanaka, Shoji, Young, Jared W, Gresack, Jodi E, Geyer, Mark A, Risbrough, Victoria B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174878/
https://www.ncbi.nlm.nih.gov/pubmed/21838910
http://dx.doi.org/10.1186/1744-9081-7-33