A Double-Blind Randomized Phase I Clinical Trial Targeting ALVAC-HIV Vaccine to Human Dendritic Cells

BACKGROUND: We conducted a novel pilot study comparing different delivery routes of ALVAC-HIV (vCP205), a canarypox vaccine containing HIV gene inserts: env, gag and pol. We explored the concept that direct ex vivo targeting of human dendritic cells (DC) would enhance the immune response compared to...

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Detalles Bibliográficos
Autores principales: Eller, Michael A., Slike, Bonnie M., Cox, Josephine H., Lesho, Emil, Wang, Zhining, Currier, Jeffrey R., Darden, Janice M., Polonis, Victoria R., Vahey, Maryanne T., Peel, Sheila, Robb, Merlin L., Michael, Nelson L., Marovich, Mary A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174939/
https://www.ncbi.nlm.nih.gov/pubmed/21949699
http://dx.doi.org/10.1371/journal.pone.0024254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174939/
https://www.ncbi.nlm.nih.gov/pubmed/21949699
http://dx.doi.org/10.1371/journal.pone.0024254

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