P-glycoprotein Dysfunction Contributes to Hepatic Steatosis and Obesity in Mice

Although the main role of P-glycoprotein (Pgp) is to extrude a broad range of xenochemicals and to protect the organism against xenotoxicity, it also transports a large range of endogenous lipids. Using mice lacking Pgp, we have investigated the possible involvement of Pgp in lipid homeostasis in vi...

Descripción completa

Detalles Bibliográficos
Autores principales: Foucaud-Vignault, Magali, Soayfane, Zeina, Ménez, Cécile, Bertrand-Michel, Justine, Martin, Pascal Guy Pierre, Guillou, Hervé, Collet, Xavier, Lespine, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174940/
https://www.ncbi.nlm.nih.gov/pubmed/21949682
http://dx.doi.org/10.1371/journal.pone.0023614

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174940/
https://www.ncbi.nlm.nih.gov/pubmed/21949682
http://dx.doi.org/10.1371/journal.pone.0023614

Ejemplares similares