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P-glycoprotein Dysfunction Contributes to Hepatic Steatosis and Obesity in Mice

Although the main role of P-glycoprotein (Pgp) is to extrude a broad range of xenochemicals and to protect the organism against xenotoxicity, it also transports a large range of endogenous lipids. Using mice lacking Pgp, we have investigated the possible involvement of Pgp in lipid homeostasis in vi...

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Detalles Bibliográficos
Autores principales:	Foucaud-Vignault, Magali, Soayfane, Zeina, Ménez, Cécile, Bertrand-Michel, Justine, Martin, Pascal Guy Pierre, Guillou, Hervé, Collet, Xavier, Lespine, Anne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174940/ https://www.ncbi.nlm.nih.gov/pubmed/21949682 http://dx.doi.org/10.1371/journal.pone.0023614

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