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DRhoGEF2 Regulates Cellular Tension and Cell Pulsations in the Amnioserosa during Drosophila Dorsal Closure

Coordination of apical constriction in epithelial sheets is a fundamental process during embryogenesis. Here, we show that DRhoGEF2 is a key regulator of apical pulsation and constriction of amnioserosal cells during Drosophila dorsal closure. Amnioserosal cells mutant for DRhoGEF2 exhibit a consist...

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Detalles Bibliográficos
Autores principales: Azevedo, Dulce, Antunes, Marco, Prag, Soren, Ma, Xiaoyan, Hacker, Udo, Brodland, G. Wayne, Hutson, M. Shane, Solon, Jerome, Jacinto, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174941/
https://www.ncbi.nlm.nih.gov/pubmed/21949688
http://dx.doi.org/10.1371/journal.pone.0023964