The Soluble Recombinant Neisseria meningitidis Adhesin NadA(Δ351–405) Stimulates Human Monocytes by Binding to Extracellular Hsp90

The adhesin NadA favors cell adhesion/invasion by hypervirulent Neisseria meningitidis B (MenB). Its recombinant form NadA(Δ351–405,) devoid of the outer membrane domain, is an immunogenic candidate for an anti-MenB vaccine able to stimulate monocytes, macrophages and dendritic cells. In this study...

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Detalles Bibliográficos
Autores principales: Cecchini, Paola, Tavano, Regina, Polverino de Laureto, Patrizia, Franzoso, Susanna, Mazzon, Cristina, Montanari, Paolo, Papini, Emanuele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3175003/
https://www.ncbi.nlm.nih.gov/pubmed/21949862
http://dx.doi.org/10.1371/journal.pone.0025089

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3175003/
https://www.ncbi.nlm.nih.gov/pubmed/21949862
http://dx.doi.org/10.1371/journal.pone.0025089

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