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The Soluble Recombinant Neisseria meningitidis Adhesin NadA(Δ351–405) Stimulates Human Monocytes by Binding to Extracellular Hsp90
The adhesin NadA favors cell adhesion/invasion by hypervirulent Neisseria meningitidis B (MenB). Its recombinant form NadA(Δ351–405,) devoid of the outer membrane domain, is an immunogenic candidate for an anti-MenB vaccine able to stimulate monocytes, macrophages and dendritic cells. In this study...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3175003/ https://www.ncbi.nlm.nih.gov/pubmed/21949862 http://dx.doi.org/10.1371/journal.pone.0025089 |