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Induction of transplantation tolerance converts potential effector T cells into graft-protective regulatory T cells

Naturally occurring FOXP3(+)CD4(+) Treg have a crucial role in self-tolerance. The ability to generate similar populations against alloantigens offers the possibility of preventing transplant rejection without indefinite global immunosuppression. Exposure of mice to donor alloantigens combined with...

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Detalles Bibliográficos
Autores principales: Francis, Ross S, Feng, Gang, Tha-In, Thanyalak, Lyons, Ian S, Wood, Kathryn J, Bushell, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3175037/
https://www.ncbi.nlm.nih.gov/pubmed/21243638
http://dx.doi.org/10.1002/eji.201040509