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Induction of transplantation tolerance converts potential effector T cells into graft-protective regulatory T cells
Naturally occurring FOXP3(+)CD4(+) Treg have a crucial role in self-tolerance. The ability to generate similar populations against alloantigens offers the possibility of preventing transplant rejection without indefinite global immunosuppression. Exposure of mice to donor alloantigens combined with...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
WILEY-VCH Verlag
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3175037/ https://www.ncbi.nlm.nih.gov/pubmed/21243638 http://dx.doi.org/10.1002/eji.201040509 |