Dysregulated TRK Signalling is a Therapeutic Target in CYLD Defective Tumours

Individuals with germline mutations in the tumour suppressor gene CYLD are at high risk of developing disfiguring cutaneous appendageal tumours, the defining tumour being the highly organised cylindroma. Here, we analysed CYLD mutant tumour genomes by array comparative genomic hybridisation (aCGH) a...

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Detalles Bibliográficos
Autores principales: Rajan, Neil, Elliott, Richard, Clewes, Oliver, Mackay, Alan, Reis-Filho, Jorge S., Burn, John, Langtry, James, Sieber-Blum, Maya, Lord, Christopher J., Ashworth, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3175103/
https://www.ncbi.nlm.nih.gov/pubmed/21552290
http://dx.doi.org/10.1038/onc.2011.133

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3175103/
https://www.ncbi.nlm.nih.gov/pubmed/21552290
http://dx.doi.org/10.1038/onc.2011.133

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