The effect of the histone deacetylase inhibitor M344 on BRCA1 expression in breast and ovarian cancer cells

BACKGROUND: The inhibition of Breast Cancer 1 (BRCA1) expression sensitizes breast and ovarian cancer cells to platinum chemotherapy. However, therapeutically relevant agents that target BRCA1 expression have not been identified. Our recent report suggested the potential of the histone deacetylase (...

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Detalles Bibliográficos
Autores principales: Weberpals, Johanne I, O'Brien, Anna M, Niknejad, Nima, Garbuio, Kyla D, Clark-Knowles, Katherine V, Dimitroulakos, Jim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3175148/
https://www.ncbi.nlm.nih.gov/pubmed/21854619
http://dx.doi.org/10.1186/1475-2867-11-29

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3175148/
https://www.ncbi.nlm.nih.gov/pubmed/21854619
http://dx.doi.org/10.1186/1475-2867-11-29

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