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Downregulation of TFPI in breast cancer cells induces tyrosine phosphorylation signaling and increases metastatic growth by stimulating cell motility

BACKGROUND: Increased hemostatic activity is common in many cancer types and often causes additional complications and even death. Circumstantial evidence suggests that tissue factor pathway inhibitor-1 (TFPI) plays a role in cancer development. We recently reported that downregulation of TFPI inhib...

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Detalles Bibliográficos
Autores principales: Stavik, Benedicte, Skretting, Grethe, Aasheim, Hans-Christian, Tinholt, Mari, Zernichow, Lillian, Sletten, Marit, Sandset, Per Morten, Iversen, Nina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3175223/
https://www.ncbi.nlm.nih.gov/pubmed/21849050
http://dx.doi.org/10.1186/1471-2407-11-357