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EFS shows biallelic methylation in uveal melanoma with poor prognosis as well as tissue-specific methylation

BACKGROUND: Uveal melanoma (UM) is a rare eye tumor. There are two classes of UM, which can be discriminated by the chromosome 3 status or global mRNA expression profile. Metastatic progression is predominantly originated from class II tumors or from tumors showing loss of an entire chromosome 3 (mo...

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Detalles Bibliográficos
Autores principales: Neumann, Lisa C, Weinhäusel, Andreas, Thomas, Stefanie, Horsthemke, Bernhard, Lohmann, Dietmar R, Zeschnigk, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3175225/
https://www.ncbi.nlm.nih.gov/pubmed/21871071
http://dx.doi.org/10.1186/1471-2407-11-380