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EFS shows biallelic methylation in uveal melanoma with poor prognosis as well as tissue-specific methylation
BACKGROUND: Uveal melanoma (UM) is a rare eye tumor. There are two classes of UM, which can be discriminated by the chromosome 3 status or global mRNA expression profile. Metastatic progression is predominantly originated from class II tumors or from tumors showing loss of an entire chromosome 3 (mo...
Autores principales: | Neumann, Lisa C, Weinhäusel, Andreas, Thomas, Stefanie, Horsthemke, Bernhard, Lohmann, Dietmar R, Zeschnigk, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3175225/ https://www.ncbi.nlm.nih.gov/pubmed/21871071 http://dx.doi.org/10.1186/1471-2407-11-380 |
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