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Brain-derived neurotrophic factor induces proliferation of human airway smooth muscle cells

Airway diseases such as asthma involve increased airway smooth muscle (ASM) contractility and remodelling via enhanced proliferation. Neurotrophins (NTs) such as brain-derived neurotrophic factor (BDNF), well-known in the nervous system, can regulate Ca(2+) signalling, and interact with cytokines in...

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Detalles Bibliográficos
Autores principales: Aravamudan, Bharathi, Thompson, Michael, Pabelick, Christina, Prakash, Y S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3175295/
https://www.ncbi.nlm.nih.gov/pubmed/21651720
http://dx.doi.org/10.1111/j.1582-4934.2011.01356.x