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C/EBP-δ regulates VEGF-C autocrine signaling in lymphangiogenesis and metastasis of lung cancer through HIF-1α

CCAAT/enhancer-binding protein delta (C/EBP-δ), a transcription factor, is elevated in carcinoma compared to normal tissue. This study reports a novel function of C/EBP-δ in lymphangiogenesis and tumor metastasis. Genetic deletion of C/EBP-δ in mice resulted in a significant reduction of lymphangiog...

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Detalles Bibliográficos
Autores principales: Min, Yongfen, Ghose, Sampa, Boelte, Kimberly, Li, Jingdong, Yang, Li, Lin, P. Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3175299/
https://www.ncbi.nlm.nih.gov/pubmed/21666710
http://dx.doi.org/10.1038/onc.2011.187