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In vitro centromere and kinetochore assembly on defined chromatin templates

During cell division, chromosomes are segregated to nascent daughter cells by attaching to the microtubules of the mitotic spindle through the kinetochore. Kinetochores are assembled on a specialized chromatin domain, called the centromere that is characterized by the replacement of nucleosomal hist...

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Detalles Bibliográficos
Autores principales: Guse, Annika, Carroll, Christopher W., Moree, Ben, Fuller, Colin J., Straight, Aaron F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3175311/
https://www.ncbi.nlm.nih.gov/pubmed/21874020
http://dx.doi.org/10.1038/nature10379