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Noninvasive In Vivo Quantification of Neutrophil Elastase Activity in Acute Experimental Mouse Lung Injury

We developed a neutrophil elastase-specific near-infrared fluorescence imaging agent, which, combined with fluorescence molecular tomographic imaging, allowed us to detect and quantify neutrophil elastase activity in vivo, in real time, and noninvasively in an acute model of lung injury (ALI). Signi...

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Detalles Bibliográficos
Autores principales: Kossodo, Sylvie, Zhang, Jun, Groves, Kevin, Cuneo, Garry J., Handy, Emma, Morin, Jeff, Delaney, Jeannine, Yared, Wael, Rajopadhye, Milind, Peterson, Jeffrey D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3175392/
https://www.ncbi.nlm.nih.gov/pubmed/21941648
http://dx.doi.org/10.1155/2011/581406