LXR agonist increases apoE secretion from HepG2 spheroid, together with an increased production of VLDL and apoE-rich large HDL

BACKGROUND: The physiological regulation of hepatic apoE gene has not been clarified, although the expression of apoE in adipocytes and macrophages has been known to be regulated by LXR. METHODS AND RESULTS: We investigated the effect of TO901317, a LXR agonist, on hepatic apoE production utilizing...

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Detalles Bibliográficos
Autores principales: Kurano, Makoto, Iso-O, Naoyuki, Hara, Masumi, Ishizaka, Nobukazu, Moriya, Kyoji, Koike, Kazuhiko, Tsukamoto, Kazuhisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3175460/
https://www.ncbi.nlm.nih.gov/pubmed/21819577
http://dx.doi.org/10.1186/1476-511X-10-134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3175460/
https://www.ncbi.nlm.nih.gov/pubmed/21819577
http://dx.doi.org/10.1186/1476-511X-10-134

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