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Innate Immune Responses to AAV Vectors

Gene replacement therapy by in vivo delivery of adeno-associated virus (AAV) is attractive as a potential treatment for a variety of genetic disorders. However, while AAV has been used successfully in many models, other experiments in clinical trials and in animal models have been hampered by undesi...

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Detalles Bibliográficos
Autores principales: Rogers, Geoffrey L., Martino, Ashley T., Aslanidi, George V., Jayandharan, Giridhara R., Srivastava, Arun, Herzog, Roland W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3175613/
https://www.ncbi.nlm.nih.gov/pubmed/21954398
http://dx.doi.org/10.3389/fmicb.2011.00194