Next-Generation Sequencing Reveals HIV-1-Mediated Suppression of T Cell Activation and RNA Processing and Regulation of Noncoding RNA Expression in a CD4(+) T Cell Line

Next-generation sequencing (NGS) enables the highly sensitive measurement of whole transcriptomes. We report the first application to our knowledge of this technology to the analysis of RNA from a CD4(+) T cell line infected with intact HIV. We sequenced the total mRNA from infected cells and detect...

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Detalles Bibliográficos
Autores principales: Chang, Stewart T., Sova, Pavel, Peng, Xinxia, Weiss, Jeffrey, Law, G. Lynn, Palermo, Robert E., Katze, Michael G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3175625/
https://www.ncbi.nlm.nih.gov/pubmed/21933919
http://dx.doi.org/10.1128/mBio.00134-11

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3175625/
https://www.ncbi.nlm.nih.gov/pubmed/21933919
http://dx.doi.org/10.1128/mBio.00134-11

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