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Stress-Induced Loss of Heterozygosity in Candida: a Possible Missing Link in the Ability to Evolve
Diploid organisms are buffered against the effects of mutations by carrying two sets of each gene, which allows compensation if one is mutated. But recombination between “mom” and “dad” chromosomes causes loss of heterozygosity (LOH), stretches of “mom-only” or “dad-only” DNA sequence, suddenly reve...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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American Society of Microbiology
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3175628/ https://www.ncbi.nlm.nih.gov/pubmed/21933916 http://dx.doi.org/10.1128/mBio.00200-11 |