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Pathways of Resistance to Thymineless Death in Escherichia coli and the Function of UvrD
Thymineless death (TLD) is the rapid loss of viability in bacterial, yeast, and human cells starved of thymine. TLD is the mode of action of common anticancer drugs and some antibiotics. TLD in Escherichia coli is accompanied by blocked replication and chromosomal DNA loss and recent work identified...
Autores principales: | Fonville, Natalie C., Vaksman, Zalman, DeNapoli, Jessica, Hastings, P. J., Rosenberg, Susan M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176125/ https://www.ncbi.nlm.nih.gov/pubmed/21705756 http://dx.doi.org/10.1534/genetics.111.130161 |
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