A cell factory of Bacillus subtilis engineered for the simple bioconversion of myo-inositol to scyllo-inositol, a potential therapeutic agent for Alzheimer's disease

BACKGROUND: A stereoisomer of inositol, scyllo-inositol, is known as a promising therapeutic agent for Alzheimer's disease, since it prevents the accumulation of beta-amyloid deposits, a hallmark of the disease. However, this compound is relatively rare in nature, whereas another stereoisomer o...

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Detalles Bibliográficos
Autores principales: Yamaoka, Masaru, Osawa, Shin, Morinaga, Tetsuro, Takenaka, Shinji, Yoshida, Ken-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176187/
https://www.ncbi.nlm.nih.gov/pubmed/21896210
http://dx.doi.org/10.1186/1475-2859-10-69

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176187/
https://www.ncbi.nlm.nih.gov/pubmed/21896210
http://dx.doi.org/10.1186/1475-2859-10-69

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