Region-specific tauopathy and synucleinopathy in brain of the alpha-synuclein overexpressing mouse model of Parkinson's disease

BACKGROUND: α-synuclein [α-Syn]-mediated activation of GSK-3β leading to increases in hyperphosphorylated Tau has been shown by us to occur in striata of Parkinson's diseased [PD] patients and in animal models of PD. In Alzheimer's disease, tauopathy exists in several brain regions; howeve...

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Detalles Bibliográficos
Autores principales: Kaul, Tiffany, Credle, Joel, Haggerty, Thomas, Oaks, Adam W, Masliah, Eliezer, Sidhu, Anita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176190/
https://www.ncbi.nlm.nih.gov/pubmed/21812967
http://dx.doi.org/10.1186/1471-2202-12-79

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176190/
https://www.ncbi.nlm.nih.gov/pubmed/21812967
http://dx.doi.org/10.1186/1471-2202-12-79

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