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Phytoceramide and sphingoid bases derived from brewer's yeast Saccharomyces pastorianus activate peroxisome proliferator-activated receptors

BACKGROUND: Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors that regulate lipid and glucose metabolism. PPARα is highly expressed in the liver and controls genes involved in lipid catabolism. We previously reported that synthetic sphingolipid analogs, p...

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Detalles Bibliográficos
Autores principales: Murakami, Itsuo, Wakasa, Yukari, Yamashita, Shinji, Kurihara, Toshio, Zama, Kota, Kobayashi, Naoyuki, Mizutani, Yukiko, Mitsutake, Susumu, Shigyo, Tatsuro, Igarashi, Yasuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176198/
https://www.ncbi.nlm.nih.gov/pubmed/21861924
http://dx.doi.org/10.1186/1476-511X-10-150