A Phase 1 Trial of MSP2-C1, a Blood-Stage Malaria Vaccine Containing 2 Isoforms of MSP2 Formulated with Montanide® ISA 720

BACKGROUND: In a previous Phase 1/2b malaria vaccine trial testing the 3D7 isoform of the malaria vaccine candidate Merozoite surface protein 2 (MSP2), parasite densities in children were reduced by 62%. However, breakthrough parasitemias were disproportionately of the alternate dimorphic form of MS...

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Detalles Bibliográficos
Autores principales: McCarthy, James S., Marjason, Joanne, Elliott, Suzanne, Fahey, Paul, Bang, Gilles, Malkin, Elissa, Tierney, Eveline, Aked-Hurditch, Hayley, Adda, Christopher, Cross, Nadia, Richards, Jack S., Fowkes, Freya J. I., Boyle, Michelle J., Long, Carole, Druilhe, Pierre, Beeson, James G., Anders, Robin F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176224/
https://www.ncbi.nlm.nih.gov/pubmed/21949716
http://dx.doi.org/10.1371/journal.pone.0024413

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176224/
https://www.ncbi.nlm.nih.gov/pubmed/21949716
http://dx.doi.org/10.1371/journal.pone.0024413

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