Cargando…

A Phase 1 Trial of MSP2-C1, a Blood-Stage Malaria Vaccine Containing 2 Isoforms of MSP2 Formulated with Montanide® ISA 720

BACKGROUND: In a previous Phase 1/2b malaria vaccine trial testing the 3D7 isoform of the malaria vaccine candidate Merozoite surface protein 2 (MSP2), parasite densities in children were reduced by 62%. However, breakthrough parasitemias were disproportionately of the alternate dimorphic form of MS...

Descripción completa

Detalles Bibliográficos
Autores principales:	McCarthy, James S., Marjason, Joanne, Elliott, Suzanne, Fahey, Paul, Bang, Gilles, Malkin, Elissa, Tierney, Eveline, Aked-Hurditch, Hayley, Adda, Christopher, Cross, Nadia, Richards, Jack S., Fowkes, Freya J. I., Boyle, Michelle J., Long, Carole, Druilhe, Pierre, Beeson, James G., Anders, Robin F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176224/ https://www.ncbi.nlm.nih.gov/pubmed/21949716 http://dx.doi.org/10.1371/journal.pone.0024413

Ejemplares similares

Safety and Immunogenicity of a Malaria Vaccine, Plasmodium falciparum AMA-1/MSP-1 Chimeric Protein Formulated in Montanide ISA 720 in Healthy Adults
por: Hu, Jinhong, et al.
Publicado: (2008)

Safety data of Montanide ISA 51 VG and Montanide ISA 720 VG, two adjuvants dedicated to human therapeutic vaccines
por: Ascarateil, Stephane, et al.
Publicado: (2015)

Sustained release of actives with Montanide™ ISA 51 VG and Montanide™ ISA 720 VG, two adjuvants dedicated to human therapeutic vaccines
por: Ascarateil, Stephane, et al.
Publicado: (2015)

Immune System Modulation by the Adjuvants Poly (I:C) and Montanide ISA 720
por: Marques, Rodolfo F., et al.
Publicado: (2022)

Cancer Vaccination against Extracellular Vimentin Efficiently Adjuvanted with Montanide ISA 720/CpG
por: van Loon, Karlijn, et al.
Publicado: (2022)

Evaluation of Four Adjuvant Combinations, IVAX-1, IVAX-2, CpG-1826+Montanide ISA 720 VG and CpG-1018+Montanide ISA 720 VG, for Safety and for Their Ability to Elicit Protective Immune Responses in Mice against a Respiratory Challenge with Chlamydia muridarum
por: Pal, Sukumar, et al.
Publicado: (2023)

Safety and Immunogenicity of a Recombinant Plasmodium falciparum AMA1 Malaria Vaccine Adjuvanted with Alhydrogel™, Montanide ISA 720 or AS02
por: Roestenberg, Meta, et al.
Publicado: (2008)

MSP For Dummies
por: Ferguson, Alan
Publicado: (2014)

Modulation of Antibody Responses against Gnathostoma spinigerum in Mice Immunized with Crude Antigen Formulated in CpG Oligonucleotide and Montanide ISA720
por: Intapan, Pewpan M., et al.
Publicado: (2013)

Temporal changes in genetic diversity of msp-1, msp-2, and msp-3 in Plasmodium falciparum isolates from Grande Comore Island after introduction of ACT
por: Huang, Bo, et al.
Publicado: (2018)

Plasmodium falciparum msp1, msp2 and glurp allele frequency and diversity in sub-Saharan Africa
por: Mwingira, Felista, et al.
Publicado: (2011)

Genetic diversity of the msp-1, msp-2, and glurp genes of Plasmodium falciparum isolates in Northwest Ethiopia
por: Mohammed, Hussein, et al.
Publicado: (2018)

Genomic miscellany and allelic frequencies of Plasmodium falciparum msp-1, msp-2 and glurp in parasite isolates
por: Ullah, Ibrar, et al.
Publicado: (2022)

Pre-Clinical Assessment of Novel Multivalent MSP3 Malaria Vaccine Constructs
por: Bang, Gilles, et al.
Publicado: (2011)

Genetic diversity of Plasmodium falciparum isolates from Pahang, Malaysia based on MSP-1 and MSP-2 genes
por: Atroosh, Wahib M, et al.
Publicado: (2011)

A vaccine consisting of Schistosoma mansoni cathepsin B formulated in Montanide ISA 720 VG induces high level protection against murine schistosomiasis
por: Ricciardi, Alessandra, et al.
Publicado: (2016)

Quantifying the Importance of MSP1-19 as a Target of Growth-Inhibitory and Protective Antibodies against Plasmodium falciparum in Humans
por: Wilson, Danny W., et al.
Publicado: (2011)

Genetic Polymorphism of msp1 and msp2 in Plasmodium falciparum Isolates from Côte d'Ivoire versus Gabon
por: Yavo, William, et al.
Publicado: (2016)

Allelic diversity of MSP1 and MSP2 repeat loci correlate with levels of malaria endemicity in Senegal and Nigerian populations
por: Oboh, Mary A., et al.
Publicado: (2021)

Plasmodium falciparum Genetic Diversity in Panamá Based on glurp, msp-1 and msp-2 Genes: Implications for Malaria Elimination in Mesoamerica
por: Santamaría, Ana María, et al.
Publicado: (2020)

Low Allelic Variation of Plasmodium falciparum msp-1 and msp-2 among Gold Miners in Central Kalimantan Province, Indonesia
por: Arwati, Heny, et al.
Publicado: (2023)

MSP430 microcontroller basics
por: Davies, J H
Publicado: (2008)

Genetic Diversity of Plasmodium vivax in Clinical Isolates from Southern Thailand using PvMSP1, PvMSP3 (PvMSP3α, PvMSP3β) Genes and Eight Microsatellite Markers
por: Thanapongpichat, Supinya, et al.
Publicado: (2019)

Phase 1 Trial of Malaria Transmission Blocking Vaccine Candidates Pfs25 and Pvs25 Formulated with Montanide ISA 51
por: Wu, Yimin, et al.
Publicado: (2008)

Genetic diversity and allele frequencies of Plasmodium falciparum msp1 and msp2 in parasite isolates from Bioko Island, Equatorial Guinea
por: Chen, Jiang-Tao, et al.
Publicado: (2018)

LigA formulated in AS04 or Montanide ISA720VG induced superior immune response compared to alum, which correlated to protective efficacy in a hamster model of leptospirosis
por: Varma, Vivek P., et al.
Publicado: (2022)

Improving Methods for Analyzing Antimalarial Drug Efficacy Trials: Molecular Correction Based on Length-Polymorphic Markers msp-1, msp-2, and glurp
por: Jones, S., et al.
Publicado: (2019)

Allelic diversity of merozoite surface protein genes (msp1 and msp2) and clinical manifestations of Plasmodium falciparum malaria cases in Aceh, Indonesia
por: Jamil, Kurnia Fitri, et al.
Publicado: (2021)

MSP Survival Guide for Programme Managers
por: AXELOS
Publicado: (2016)

Getting started with the MSP430 Launchpad
por: Fernandez, Adrian, et al.
Publicado: (2013)

MSP® programme management practitioner courseware
por: Brolsma, Douwe, et al.
Publicado: (2019)

Phase 1 Study of Two Merozoite Surface Protein 1 (MSP1(42)) Vaccines for Plasmodium falciparum Malaria
por: Malkin, Elissa, et al.
Publicado: (2007)

Genetic diversity of msp3α and msp1_b5 markers of Plasmodium vivax in French Guiana
por: Véron, Vincent, et al.
Publicado: (2009)

Genetic polymorphism of Merozoite Surface Protein 1 (msp1) and 2 (msp2) genes and multiplicity of Plasmodium falciparum infection across various endemic areas in Senegal
por: Ndiaye, Tolla, et al.
Publicado: (2019)

Status of allele frequency and diversity of Plasmodium falciparum msp1, msp2 and glurp before implementation of an artemisinin-based combined therapy in Northwestern Colombia.
por: Maestre, Amanda, et al.
Publicado: (2013)

Comparative study of Plasmodium falciparum msp-1 and msp-2 Genetic Diversity in Isolates from Rural and Urban Areas in the South of Brazzaville, Republic of Congo
por: Baina, Marcel Tapsou, et al.
Publicado: (2023)

Evaluation of Montanide™ ISA 71 VG Adjuvant during Profilin Vaccination against Experimental Coccidiosis
por: Jang, Seung I., et al.
Publicado: (2013)

A Comparison of MGMT Testing by MSP and qMSP in Paired Snap-Frozen and Formalin-Fixed Paraffin-Embedded Gliomas
por: Lazarević, Milica, et al.
Publicado: (2023)

Genetic Diversity of Polymorphic Marker Merozoite Surface Protein 1 (Msp-1) and 2 (Msp-2) Genes of Plasmodium falciparum Isolates From Malaria Endemic Region of Pakistan
por: Khan, Shahid Niaz, et al.
Publicado: (2021)

Genetic diversity of Plasmodium falciparum isolates based on MSP-1 and MSP-2 genes from Kolla-Shele area, Arbaminch Zuria District, southwest Ethiopia
por: Mohammed, Hussein, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_79726j8kopkl85vgq9cll6f74k