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Inhibition of HIV-1 Infection in Ex Vivo Cervical Tissue Model of Human Vagina by Palmitic Acid; Implications for a Microbicide Development

BACKGROUND: Approximately 80% of all new HIV-1 infections are acquired through sexual contact. Currently, there is no clinically approved microbicide, indicating a clear and urgent therapeutic need. We recently reported that palmitic acid (PA) is a novel and specific inhibitor of HIV-1 fusion and en...

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Detalles Bibliográficos
Autores principales: Lin, Xudong, Paskaleva, Elena E., Chang, William, Shekhtman, Alexander, Canki, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176227/
https://www.ncbi.nlm.nih.gov/pubmed/21949756
http://dx.doi.org/10.1371/journal.pone.0024803