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The BH3 mimetic ABT-737 increases treatment efficiency of paclitaxel against hepatoblastoma

BACKGROUND: The primary goal of current chemotherapy in hepatoblastoma (HB) is reduction of tumour volume and vitality to enable complete surgical resection and reduce risk of recurrence or metastatic disease. Drug resistance remains a major challenge for HB treatment. In some malignancies inhibitio...

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Detalles Bibliográficos
Autores principales: Lieber, Justus, Eicher, Carmen, Wenz, Julia, Kirchner, Bettina, Warmann, Steven W, Fuchs, Jörg, Armeanu-Ebinger, Sorin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176244/
https://www.ncbi.nlm.nih.gov/pubmed/21854558
http://dx.doi.org/10.1186/1471-2407-11-362