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A genomic biomarker signature can predict skin sensitizers using a cell-based in vitro alternative to animal tests
BACKGROUND: Allergic contact dermatitis is an inflammatory skin disease that affects a significant proportion of the population. This disease is caused by an adverse immune response towards chemical haptens, and leads to a substantial economic burden for society. Current test of sensitizing chemical...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176258/ https://www.ncbi.nlm.nih.gov/pubmed/21824406 http://dx.doi.org/10.1186/1471-2164-12-399 |