Cargando…
A genomic biomarker signature can predict skin sensitizers using a cell-based in vitro alternative to animal tests
BACKGROUND: Allergic contact dermatitis is an inflammatory skin disease that affects a significant proportion of the population. This disease is caused by an adverse immune response towards chemical haptens, and leads to a substantial economic burden for society. Current test of sensitizing chemical...
Autores principales: | Johansson, Henrik, Lindstedt, Malin, Albrekt, Ann-Sofie, Borrebaeck, Carl AK |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176258/ https://www.ncbi.nlm.nih.gov/pubmed/21824406 http://dx.doi.org/10.1186/1471-2164-12-399 |
Ejemplares similares
-
Prediction of Chemical Respiratory Sensitizers Using GARD, a Novel In Vitro Assay Based on a Genomic Biomarker Signature
por: Forreryd, Andy, et al.
Publicado: (2015) -
Skin sensitizers differentially regulate signaling pathways in MUTZ-3 cells in relation to their individual potency
por: Albrekt, Ann-Sofie, et al.
Publicado: (2014) -
Evaluation of high throughput gene expression platforms using a genomic biomarker signature for prediction of skin sensitization
por: Forreryd, Andy, et al.
Publicado: (2014) -
Skin Sensitization Testing—What’s Next?
por: Grundström, Gunilla, et al.
Publicado: (2019) -
Transcriptional Profiling of Human Dendritic Cell Populations and Models - Unique Profiles of In Vitro Dendritic Cells and Implications on Functionality and Applicability
por: Lundberg, Kristina, et al.
Publicado: (2013)