Epigenetic Regulation of MicroRNA Genes and the Role of miR-34b in Cell Invasion and Motility in Human Melanoma

Invasive melanoma is the most lethal form of skin cancer. The treatment of melanoma-derived cell lines with 5-aza-2′-deoxycytidine (5-Aza-dC) markedly increases the expression of several miRNAs, suggesting that the miRNA-encoding genes might be epigenetically regulated, either directly or indirectly...

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Detalles Bibliográficos
Autores principales: Mazar, Joseph, Khaitan, Divya, DeBlasio, Dan, Zhong, Cuncong, Govindarajan, Subramaniam S., Kopanathi, Sharmila, Zhang, Shaojie, Ray, Animesh, Perera, Ranjan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176288/
https://www.ncbi.nlm.nih.gov/pubmed/21949788
http://dx.doi.org/10.1371/journal.pone.0024922

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176288/
https://www.ncbi.nlm.nih.gov/pubmed/21949788
http://dx.doi.org/10.1371/journal.pone.0024922

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