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Epigenetic Regulation of MicroRNA Genes and the Role of miR-34b in Cell Invasion and Motility in Human Melanoma
Invasive melanoma is the most lethal form of skin cancer. The treatment of melanoma-derived cell lines with 5-aza-2′-deoxycytidine (5-Aza-dC) markedly increases the expression of several miRNAs, suggesting that the miRNA-encoding genes might be epigenetically regulated, either directly or indirectly...
Autores principales: | Mazar, Joseph, Khaitan, Divya, DeBlasio, Dan, Zhong, Cuncong, Govindarajan, Subramaniam S., Kopanathi, Sharmila, Zhang, Shaojie, Ray, Animesh, Perera, Ranjan J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176288/ https://www.ncbi.nlm.nih.gov/pubmed/21949788 http://dx.doi.org/10.1371/journal.pone.0024922 |
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