Receptor-Mediated Endocytosis of α-Galactosidase A in Human Podocytes in Fabry Disease

Injury to the glomerular podocyte is a key mechanism in human glomerular disease and podocyte repair is an important therapeutic target. In Fabry disease, podocyte injury is caused by the intracellular accumulation of globotriaosylceramide. This study identifies in the human podocyte three endocytic...

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Detalles Bibliográficos
Autores principales: Prabakaran, Thaneas, Nielsen, Rikke, Larsen, Jakob V., Sørensen, Søren S., Rasmussen, Ulla Feldt-, Saleem, Moin A., Petersen, Claus M., Verroust, Pierre J., Christensen, Erik I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176300/
https://www.ncbi.nlm.nih.gov/pubmed/21949853
http://dx.doi.org/10.1371/journal.pone.0025065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176300/
https://www.ncbi.nlm.nih.gov/pubmed/21949853
http://dx.doi.org/10.1371/journal.pone.0025065

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