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Rhythmic Leptin Is Required for Weight Gain from Circadian Desynchronized Feeding in the Mouse

The neuroendocrine and metabolic effects of leptin have been extensively researched since the discovery, and the later identification, of the leptin gene mutated within the ob/ob mouse. Leptin is required for optimal health in a number of physiological systems (e.g. fertility, bone density, body wei...

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Detalles Bibliográficos
Autores principales: Arble, Deanna Marie, Vitaterna, Martha Hotz, Turek, Fred W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176308/
https://www.ncbi.nlm.nih.gov/pubmed/21949859
http://dx.doi.org/10.1371/journal.pone.0025079