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Rhythmic Leptin Is Required for Weight Gain from Circadian Desynchronized Feeding in the Mouse
The neuroendocrine and metabolic effects of leptin have been extensively researched since the discovery, and the later identification, of the leptin gene mutated within the ob/ob mouse. Leptin is required for optimal health in a number of physiological systems (e.g. fertility, bone density, body wei...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176308/ https://www.ncbi.nlm.nih.gov/pubmed/21949859 http://dx.doi.org/10.1371/journal.pone.0025079 |