Performance of Genotype Imputation for Rare Variants Identified in Exons and Flanking Regions of Genes

Genotype imputation has the potential to assess human genetic variation at a lower cost than assaying the variants using laboratory techniques. The performance of imputation for rare variants has not been comprehensively studied. We utilized 8865 human samples with high depth resequencing data for t...

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Detalles Bibliográficos
Autores principales: Li, Li, Li, Yun, Browning, Sharon R., Browning, Brian L., Slater, Andrew J., Kong, Xiangyang, Aponte, Jennifer L., Mooser, Vincent E., Chissoe, Stephanie L., Whittaker, John C., Nelson, Matthew R., Ehm, Margaret Gelder
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176314/
https://www.ncbi.nlm.nih.gov/pubmed/21949800
http://dx.doi.org/10.1371/journal.pone.0024945

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176314/
https://www.ncbi.nlm.nih.gov/pubmed/21949800
http://dx.doi.org/10.1371/journal.pone.0024945

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