An ENU-Induced Mutation of Nrg1 Causes Dilated Pupils and a Reduction in Muscarinic Receptors in the Sphincter Pupillae

BACKGROUND: N-ethyl-N-nitrosourea (ENU)-induced mutagenesis is a powerful tool for the study of gene function and the generation of human disease models. A large number of mouse mutants obtained by ENU-induced mutagenesis with a variety of phenotypes have been recovered. However, after genetic confi...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Bing, Li, Ke, Zhang, Fenli, Zhai, Guoqin, Gong, Wen, Qiang, Sujing, Xue, Zhengfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176322/
https://www.ncbi.nlm.nih.gov/pubmed/21949880
http://dx.doi.org/10.1371/journal.pone.0025176

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176322/
https://www.ncbi.nlm.nih.gov/pubmed/21949880
http://dx.doi.org/10.1371/journal.pone.0025176

Ejemplares similares