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Endothelial Cells Are Central Orchestrators of Cytokine Amplification during Influenza Virus Infection

Cytokine storm during viral infection is a prospective predictor of morbidity and mortality, yet the cellular sources remain undefined. Here, using genetic and chemical tools to probe functions of the S1P(1) receptor, we elucidate cellular and signaling mechanisms that are important in initiating cy...

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Detalles Bibliográficos
Autores principales: Teijaro, John R., Walsh, Kevin B., Cahalan, Stuart, Fremgen, Daniel M., Roberts, Edward, Scott, Fiona, Martinborough, Esther, Peach, Robert, Oldstone, Michael B.A., Rosen, Hugh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176439/
https://www.ncbi.nlm.nih.gov/pubmed/21925319
http://dx.doi.org/10.1016/j.cell.2011.08.015